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FarmaKology Newsletter - Issue #71

www.farmakology.com

FarmaKology Newsletter - Issue #71

FarmaKology
Apr 20, 2021
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FarmaKology Newsletter - Issue #71

www.farmakology.com

Today's Startup

Adagio Therapeutics
Adagio Therapeutics

Adagio Therapeutics

Adagio Therapeutics, Inc. is a clinical-stage biotechnology company developing best-in-class antibodies that can broadly neutralize SARS-CoV-2, SARS-CoV-1 and additional pre-emergent coronaviruses. Our candidates are optimized using Adimab’s industry-leading antibody engineering capabilities and are designed to provide patients and clinicians with an unsurpassed combination of potency, breadth, durable protection (via half-life extension), manufacturability, tolerability, and affordability. Our portfolio of SARS-CoV-2 antibodies includes multiple, non-competing antibodies with distinct binding epitopes. Pre-clinical data show that our lead antibody ADG20 matches or exceeds the potency and coverage of other clinical SARS-CoV-2 antibody programs.

News

Johnson & Johnson COVID-19 Vaccine Roll-out to Resume in Europe Following European Medicines Agency (EMA) Review

 Johnson & Johnson today announced that the European Medicines Agency’s (EMA) Pharmacovigilance Risk Assessment Committee has provided updated guidance for use of the Company’s COVID-19 vaccine and confirmed the overall benefit-risk profile remains positive. The guidance follows a PRAC review of a small number of cases of a very rare adverse event involving blood clots in combination with low platelet counts that can occur within approximately one to three weeks following injection with the Company’s COVID-19 vaccine.

Gain Therapeutics Announces Multi-Target Drug Discovery Collaboration Agreement with Zentalis Pharmaceuticals

 Gain Therapeutics, Inc. today announced a multi-target collaboration agreement with Zentalis Pharmaceuticals to discover new product candidates for the treatment of cancer. Gain will use its proprietary SEE-Tx computational platform technology to identify new sites on target proteins for potential use in oncology. SEE-Tx applies a proprietary computational algorithm and supercomputer processing to the published 3D structure of proteins to discover new binding sites with the ability to modulate protein function.

Amgen Launches Biomarker Assist™, a Program To Help More Patients With Non-Small Cell Lung Cancer Gain Access To Biomarker Testing

 Amgen announced the launch of Biomarker Assist™, a program to help more patients with metastatic (stage IV) non-small cell lung cancer gain access to biomarker testing. Biomarker testing at the time of diagnosis is a critical first step in getting patients on the right treatment. Through Biomarker Assist™, eligible patients may save on biomarker testing.

Sorrento Announces Positive Results of Phase 1b Study of COVI-MSC™ Treatment of ICU Covid-19 Patients, Achieving 100% (10 out 10) Discharge Rate

Sorrento Therapeutics, Inc. announced today the completion of enrollment in its Phase 1b study of human allogeneic adipose-derived mesenchymal stem cells (COVI-MSC™) infusions to treat COVID-19 induced acute respiratory failure (ARD) or acute respiratory distress syndrome. This current study (MSC-COV-101) is a single-arm, non-randomized Phase 1b study of the safety and preliminary efficacy of COVI-MSCs administered every other day for up to three infusions for a total of 1 x 106 cells/kg, with patients being followed for 28 days following the final infusion.

Research & Study

Study shows how some bacteria withstand the antibiotic onslaught

New software could enable the design of DNA robots for drug delivery

Drug May Help To Regenerate Erectile Nerves Damaged by Prostate Surgery

Diabetes drug may be a valuable ally against cancer

Podcast

Listen to Ep 155 Treatment Of Bradycardia And Bradydysrhythmias and 293 more episodes by Emergency Medicine Cases, free! No signup or install needed. Ep 155 Treatment of Bradycardia and Bradydysrhythmias. Ep 154: 4-Step Approach to Bradycardia and Bradydysrhythmias.

Job Opportunities

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Upcoming Webinar

Validation strategies for cloud-based EDCs - more innovation, less effort

Adaptations and Solutions for Clinical Supply Chain Challenges

Comparison of Hybrid LCMS & Ligand Binding Assays for Bioanalysis

Video

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FarmaKology Newsletter - Issue #71

www.farmakology.com
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