By FarmaKology

FarmaKology Newsletter - Issue #71





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April 21 · Issue #71 · View online

FarmaKology is a newsletter that brings you the latest news, research, job opportunities in the Pharma world, and much more! If you would like to be featured in the newsletter, sponsor an issue, or need anything, please feel free to get in touch with me at "".

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Today's Startup
Adagio Therapeutics
Adagio Therapeutics
Adagio Therapeutics
Adagio Therapeutics, Inc. is a clinical-stage biotechnology company developing best-in-class antibodies that can broadly neutralize SARS-CoV-2, SARS-CoV-1 and additional pre-emergent coronaviruses. Our candidates are optimized using Adimab’s industry-leading antibody engineering capabilities and are designed to provide patients and clinicians with an unsurpassed combination of potency, breadth, durable protection (via half-life extension), manufacturability, tolerability, and affordability. Our portfolio of SARS-CoV-2 antibodies includes multiple, non-competing antibodies with distinct binding epitopes. Pre-clinical data show that our lead antibody ADG20 matches or exceeds the potency and coverage of other clinical SARS-CoV-2 antibody programs.
 Johnson & Johnson today announced that the European Medicines Agency’s (EMA) Pharmacovigilance Risk Assessment Committee has provided updated guidance for use of the Company’s COVID-19 vaccine and confirmed the overall benefit-risk profile remains positive. The guidance follows a PRAC review of a small number of cases of a very rare adverse event involving blood clots in combination with low platelet counts that can occur within approximately one to three weeks following injection with the Company’s COVID-19 vaccine.
 Gain Therapeutics, Inc. today announced a multi-target collaboration agreement with Zentalis Pharmaceuticals to discover new product candidates for the treatment of cancer. Gain will use its proprietary SEE-Tx computational platform technology to identify new sites on target proteins for potential use in oncology. SEE-Tx applies a proprietary computational algorithm and supercomputer processing to the published 3D structure of proteins to discover new binding sites with the ability to modulate protein function.
 Amgen announced the launch of Biomarker Assist™, a program to help more patients with metastatic (stage IV) non-small cell lung cancer gain access to biomarker testing. Biomarker testing at the time of diagnosis is a critical first step in getting patients on the right treatment. Through Biomarker Assist™, eligible patients may save on biomarker testing.
Sorrento Therapeutics, Inc. announced today the completion of enrollment in its Phase 1b study of human allogeneic adipose-derived mesenchymal stem cells (COVI-MSC™) infusions to treat COVID-19 induced acute respiratory failure (ARD) or acute respiratory distress syndrome. This current study (MSC-COV-101) is a single-arm, non-randomized Phase 1b study of the safety and preliminary efficacy of COVI-MSCs administered every other day for up to three infusions for a total of 1 x 106 cells/kg, with patients being followed for 28 days following the final infusion.
Research & Study
Ep 155 Treatment Of Bradycardia And Bradydysrhythmias Emergency Medicine Cases podcast
Job Opportunities
Upcoming Webinar
Mayo Clinic Q&A podcast: Breakthrough COVID-19 infections and booster vaccines
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